Publications and Media

Peer-reviewed Publications

For an up-to-date list see Google Scholar.

  • J James, S Towers, J Foerster, H Steel. Optimisation strategies for directed evolution without sequencing, bioRxiv, 2024 (PDF)
 
  • K Sechkar, H Steel, G Perrino, GB Stan. A coarse-grained bacterial cell model for resource-aware analysis and design of synthetic gene circuits, Nature Communications, 2024 (PDF)
  • S Towers, J James, H Steel, I Kempf. Learning-Based Estimation of Fitness Landscape Ruggedness for Directed Evolution, bioRxiv, 2024 (PDF)
  • M Denton et al. Integration of pH control into Chi.Bio reactors and demonstration with small-scale enzymatic poly(ethylene terephthalate) hydrolysis, bioRxiv, 2024 (PDF)
  • M Gasparek, H Steel, A Papachristodoulou. Deciphering mechanisms of production of natural compounds using inducer-producer microbial consortia, Biotechnology Advances, 2023 (PDF)
  • T Lee, H Steel. Cybergenetic control of microbial community composition, Frontiers in Bioengineering and Biotechnology, 2022 (PDF)
  • A Sootla et al. Dichotomous Feedback: A Signal Sequestration-based Feedback Mechanism for Biocontroller Design, Journal of the Royal Society Interface, 2022 (PDF)
  • R Beale et al. OxVent: Design and evaluation of a rapidlymanufactured Covid-19 ventilator, eBioMedicine, 2022 (PDF)
  • L Zillig, H Steel. Cells and computers, better together, Nature Reviews Microbiology, 2021 (PDF)
  • J Chen, B Lim, H Steel, Y Song, M Ji, W Huang. Redesign of ultrasensitive and robust RecA gene circuit to sense DNA damage, Microbial Biotechnology, 2021 (PDF)
  • P Rutten, H Steel, G Hood, V Ramachandran, L McMurtry, B Geddes, A Papachristodoulou, P Poole. Multiple sensors provide spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis, PLOS Genetics, 2021 (PDF)
  • H Steel, R Habgood, C Kelly, A Papachristodoulou. Chi.Bio: An open-source automated experimental platform for biological science research, PLOS Biology, 2020 (PDF)
  • H Steel, A Papachristodoulou. The effect of spatiotemporal antibiotic inhomogeneities on the evolution of resistance, Journal of Theoretical Biology, 2019 (PDF)

  • H Steel, A Papachristodoulou. Low-burden biological feedback controllers for near-perfect adaptation, ACS Synthetic Biology, 2019 (PDF)

  • H Steel, A Sootla, N Delalez, A Papachristodoulou. Mitigating Biological Signalling Cross-talk with Feedback Control, Proceedings of the European Control Conference, 2019 (PDF)

  • J Chen, H Steel, YH Wu, Y Wang, J Xu, CPN Rampley, IP Thompson, A Papachristodoulou, WE Huang. Development of Aspirin-Inducible Biosensors in Escherichia coli and SimCells, Applied Environmental Microbiology, 2019 (PDF)

  • H Steel, A Sootla, B Smart, N Delalez, A Papachristodoulou. Improving Orthogonality in Two-Component Biological Signalling Systems using Feedback Control, IEEE Control Systems Letters, 2018 (PDF)

  • C Kelly, A Harris, H Steel, EJ Hancock, JT Heap, A Papachristodoulou. Synthetic negative feedback circuits using engineered small RNAs, Nucleic Acids Research, 2018 (PDF)

  • H Steel, A Papachristodoulou. Probing Inter-Cell Variability using Bulk Measurements, ACS Synthetic Biology, 2018 (PDF)

  • H Steel, A Papachristodoulou. Design constraints for biological systems that achieve adaptation and disturbance rejection, IEEE Transactions on Control of Network Systems, 2018 (PDF)

  • A Harris, C Kelly, H Steel, A Papachristodoulou. The autorepressor: A case study of the importance of model selection, 2017 IEEE Conference on Decision and Control, 2017 (PDF)

  • H Steel, G Lillacci, M Khammash, A Papachristodoulou. Challenges at the interface of control engineering and synthetic biology, 2017 IEEE Conference on Decision and Control, 2017 (PDF)

  • H Steel, AWK Harris, AJ Hancock, CL Kelly, A Papachristodoulou. Frequency domain analysis of small non-coding RNAs shows summing junction-like behaviour, 2017 IEEE Conference on Decision and Control, 2017 (PDF)

  • T Folliard, B Mertins, H Steel, TP Prescott, T Newport, CW Jones, G Wadhams, T Bayer, JP Armitage, A Papachristodoulou, LJ Rothschild. Ribo-attenuators: novel elements for reliable and modular riboswitch engineering, Scientific Reports, 2017 (PDF)

  • T Folliard, H Steel, TP Prescott, G Wadhams, LJ Rothschild, A Papachristodoulou. A synthetic recombinase-based feedback loop results in robust expression, ACS Synthetic Biology, 2017 (PDF)

  • H Steel, A Papachristodoulou. Feedback Control and Synthetic Biology: Constraints on Design, Proceedings of the 2017 IFAC World Congress, 2017 (PDF)

  • A Aschikhin et al. The FLASHForward Facility at DESY, Nuclear Instruments and Methods in Physics Research, 2016 (PDF)

  • H Steel, C McKay, D Andersen. Modeling circulation and seasonal fluctuations in perennially ice-covered and ice-walled Lake Untersee, Antarctica, Limnology & Oceanography, 2015 (PDF)

  • H Steel et al. The internal-external respiratory motion correlation is unaffected by audiovisual biofeedback, Australasian Physical & Engineering Sciences in Medicine, 2014

  • D Willson et al. Performance of field scientists undertaking observations of early life fossils while in a simulated space suit, Acta Astronautica, 2013

  • P Gong, H Steel, P Robinson, Y Qi. Dynamic patterns and their interactions in networks of excitable elements, Physical Review E, 2013

In the Media